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Topic: Coronavirus - part 2
Kevin's photo
Mon 04/26/21 04:03 AM

http://www.bloomberg.com/news/articles/2021-04-24/u-s-states-relaunch-j-j-shot-after-10-day-halt-virus-update

Distressing to see what is unfolding in India . Finally the world is starting to take notice and send much needed aid .

It's truly horrifying here

SparklingCrystal πŸ’–πŸ’Ž's photo
Wed 04/28/21 05:56 AM
Finally no more curfew, and restaurant terraces are allowed to open again! Both as of today! And we can go to shops without having to make an appointment!!

Feels like freedom after prison time.

no photo
Wed 04/28/21 11:01 PM


http://www.bloomberg.com/news/articles/2021-04-24/u-s-states-relaunch-j-j-shot-after-10-day-halt-virus-update

Distressing to see what is unfolding in India . Finally the world is starting to take notice and send much needed aid .

It's truly horrifying here
I feel very fortunate to be in New Zealand but my heart and thoughts are with all those in India . Take care of each other and do whatever you can to stay strong and safe x

no photo
Fri 04/30/21 04:24 PM
My second dose of the Pfizer vaccine has been booked .. yay ., doing cartwheels :angel: waving

no photo
Sat 05/01/21 02:23 PM

Pay Attention People!!!
Girlfriend and I went to the store with our masks on,
Got home took off masks,
And brought home the wrong girlfriend.
congrats on finding a girlfriend ..is that a recent success ??? If so , perhaps you are the one who needs to pay more attention :wink:

SparklingCrystal πŸ’–πŸ’Ž's photo
Sat 05/08/21 02:38 AM
Seems that so far the US is about the only sane country left in the world? Partially then, with a number of states that do not allow a vaccine passport.

Over here a platform is being formed now for people who exercise their birth-right to freedom so they still can have access to healthcare, shops etc.

It's insane the world is coming to this. Some even want to go as far as having to show a vaccine passport to attend a wedding? WTF?

Some argue that proof of vaccines has always existed. And that's correct. But NOT to attend an event, a wedding, a funeral, nor for travel within normally healthy countries like mine, the US, Germany, UK, France etc. etc.
Nor did we ever have to show vaccine credentials to enter a shop.

So I'm glad there's this platform.
Of late I'm thinking about what Diana Cooper said years ago, that we will get New Golden Communities. And thinking that this may be the only way out for us natural people. To live in our own communities, away from the judgemental people that don't think twice about violating human rights of others.

SparklingCrystal πŸ’–πŸ’Ž's photo
Sat 05/08/21 02:48 AM

@crystal .. re nothing to fear ... does that mean If you required hospitalisation for a non covid event that you would be happy to be warded with covid /potential covid patients if there was a capacity issue at the hospital ????

Lemme see... would you want to be put in a room with someone that has ebola/measles/leprosy/flu etc. etc. ?
I'm quite certain the answer is "No".
Does that mean you live in fear of getting ebola, measles, leprosy, flu?

The fact that a disease CAN be tricky to some doesn't mean you live in fear of getting it.

Rock's photo
Sun 05/09/21 03:07 PM

My second dose of the Pfizer vaccine has been booked .. yay ., doing cartwheels :angel: waving


If we turn into vaxx zombies,
let's hit the elite universities first.
devil

My second dose of Pfizer was in late March.
laugh

no photo
Sun 05/09/21 03:36 PM
Have you noted that influenza has almost disappeared during the covid event?

Every one has been not mixing that's why.

A billion people get flue every year ( according to the WHO)

Think covid ,150.000,000 would have been probably as influenza 1000,000,0000.

In a year if firm measures had not been taken to control the spread.

no photo
Fri 05/14/21 01:55 PM
How surprising are the vaccinated Yankees’ COVID-19 cases? Experts explain the implications

https://www.yahoo.com/sports/how-surprising-are-the-vaccinated-yankees-covid-19-cases-experts-explain-the-implications-030355895.html

no photo
Fri 05/14/21 02:22 PM
Edited by Blondey111 on Fri 05/14/21 02:23 PM


@crystal .. re nothing to fear ... does that mean If you required hospitalisation for a non covid event that you would be happy to be warded with covid /potential covid patients if there was a capacity issue at the hospital ????

Lemme see... would you want to be put in a room with someone that has ebola/measles/leprosy/flu etc. etc. ?
I'm quite certain the answer is "No".
Does that mean you live in fear of getting ebola, measles, leprosy, flu?

The fact that a disease CAN be tricky to some doesn't mean you live in fear of getting it.
actually i am frequently in rooms with highly infectious pathogens ., including new and unknown . .. I am highly skilled and know how to keep my self safe ... Perhaps you should have just been honest and answered the question from your own perspective .. instead of deflecting to me .. :wink:

no photo
Fri 05/14/21 02:27 PM


My second dose of the Pfizer vaccine has been booked .. yay ., doing cartwheels :angel: waving


If we turn into vaxx zombies,
let's hit the elite universities first.
devil

My second dose of Pfizer was in late March.
laugh
making me laugh ... perhaps we will become randy vampires instead of zombies .. sounds a little more fun biggrin

no photo
Fri 05/14/21 02:30 PM

Have you noted that influenza has almost disappeared during the covid event?

Every one has been not mixing that's why.

A billion people get flue every year ( according to the WHO)

Think covid ,150.000,000 would have been probably as influenza 1000,000,0000.

In a year if firm measures had not been taken to control the spread.
I certainly noticed . Also a decrease in community acquired pneumonia and hospital related admissions in general ... during our short lockdown . Was surreal to witness .

no photo
Fri 05/14/21 02:38 PM

How surprising are the vaccinated Yankees’ COVID-19 cases? Experts explain the implications

https://www.yahoo.com/sports/how-surprising-are-the-vaccinated-yankees-covid-19-cases-experts-explain-the-implications-030355895.html
Hi Alexandria waving some countries have rejected the Johnson and Johnson vaccine which was the vaccine the Yankees team received . Sounds like they are still trying to investigate how and why the infection happened 14 days after vaccination . It is possible one or more of the players was already incubating covid at the time of vaccination .. or as stated in the article contact with a different strain of covid .. or issues with the level of immunity the one shot J&J vaccine provides . Still under investigation .

jaish's photo
Tue 05/18/21 07:51 PM
Wonder drug '2 DG' for those already infected. It's available in powder form and described as 'oral vaccine' - developed by Defense Research Lab in India.


β€œ2-DG accumulates in the virus-infected cells and prevents virus growth by stopping viral synthesis and energy production. Its selective accumulation in virally infected cells makes this drug unique,” Dr Reddy maintained.

He said 51 per cent of the patients were cured within three days during the third phase of clinical trials and others within 5 to 7 days after administering the drug, which can be used for moderate to severe Covid patients.

It is a generic molecule and it can be produced in any country, he informed. On production plans, he said they have been discussing bulk production and they would come out with an action plan within the next two or three days.

no photo
Tue 05/18/21 09:59 PM

Wonder drug '2 DG' for those already infected. It's available in powder form and described as 'oral vaccine' - developed by Defense Research Lab in India.


β€œ2-DG accumulates in the virus-infected cells and prevents virus growth by stopping viral synthesis and energy production. Its selective accumulation in virally infected cells makes this drug unique,” Dr Reddy maintained.

He said 51 per cent of the patients were cured within three days during the third phase of clinical trials and others within 5 to 7 days after administering the drug, which can be used for moderate to severe Covid patients.

It is a generic molecule and it can be produced in any country, he informed. On production plans, he said they have been discussing bulk production and they would come out with an action plan within the next two or three days.

Hi Jai ... I have been unable to find the phase three clinical trial data ... only a press release from the defence force and government . ..

In the past, 2G has been researched as a cancer treatment , however from what I have read , no approval has been granted .

Media Sources in India are claiming 2G is safe .. .yet in the past there have been concerns with dose dependent prolonged QT and cardiac events .

If you are able to source the phase three clinical trial info would be interested in reading . waving






jaish's photo
Wed 05/19/21 07:07 PM
Edited by jaish on Wed 05/19/21 07:09 PM
Over here, for home grown drugs meant for home applications, third phase trial data is generally not presented in the clinical form you maybe looking for.

What we have are from press releases.

3rd Phase: From December to mid-March this year, 2-DG drugs were given to 220 patients in 27 hospitals in Delhi, UP, ....; clinical trials submitted the complete data to DCGI on May 1 and sought permission for emergency use.

The DCGI, which reviewed the results, approved.

https://www.thehansindia.com/news/national/drdos-2dg-drug-here-is-all-you-need-to-know-about-the-anti-covid-19-drug-685872

---xx

General info for members:

2G is a drug and not a vaccine.
What the drug does is freeze the infected cells and starve the virus so that it cannot replicate. In other words, the drug's mechanism helps in reduced need for oxygen, and faster recovery.

The drug is meant for covid patients and more so if covid comes after vaccination.

In other words, it is not a substitute for vaccination.


no photo
Wed 05/19/21 11:23 PM

Over here, for home grown drugs meant for home applications, third phase trial data is generally not presented in the clinical form you maybe looking for.

What we have are from press releases.

3rd Phase: From December to mid-March this year, 2-DG drugs were given to 220 patients in 27 hospitals in Delhi, UP, ....; clinical trials submitted the complete data to DCGI on May 1 and sought permission for emergency use.

The DCGI, which reviewed the results, approved.

https://www.thehansindia.com/news/national/drdos-2dg-drug-here-is-all-you-need-to-know-about-the-anti-covid-19-drug-685872

---xx

General info for members:

2G is a drug and not a vaccine.
What the drug does is freeze the infected cells and starve the virus so that it cannot replicate. In other words, the drug's mechanism helps in reduced need for oxygen, and faster recovery.

The drug is meant for covid patients and more so if covid comes after vaccination.

In other words, it is not a substitute for vaccination.


hi jai .

phase iii clinical trial data release is important to determine the validity and efficacy of the study Without it 2DG use would likely be limited to India .

To highlight my concerns .. I read a claim that the study was not blinded . Which means the researchers knew who was being given the treatment and who was on the standard arm . Not claiming this is true .....but if it is . ... That introduces bias to the study results .
Without knowing the statistical significance of results . The percentages quoted above are meaningless . It is not enough to claim a treatment is safe ... they need to show evidence and transparency .

Do you know if the phase iii trial was registered?? it is usual for such trials to be registered and approved through a recognised research authority .

An earlier study , which trialled 2DG β€˜s therapeutic use to treat cancer cells suggested a dose of 63mg/kg/day as capable of causing cardiac side effects .
According to the article below .. India’s phase iib trial was based on an optimal dose of 90mg/kg .. do you know what dose has been recommended ??

http://theprint.in/health/dr-reddys-potential-cancer-drug-shows-promise-against-covid-gets-nod-for-phase-3-trial/524185/?amp

What reassurance is given that 2DG is not harmful to or accumulated by cells other than the virus.

http://thefederal.com/covid-19/drdo-drug-for-covid/amp/

As with any new therapy there will be lots of questions .., I truly hope India have found a successful intervention :heart: Hopefully more clinical information will be forthcoming :-)



Tom4Uhere's photo
Thu 05/20/21 07:24 AM
My gf goes for her second dose tomorrow.
My son told me he had his second dose a few weeks ago and felt pain in his chest and back for a day or two but it went away on its own.
I don't know which vacc they had.

The VA is pestering me to get mine.
I'm on the fence about the whole thing.
Not only is my health not so good I have respiratory problems like copp and bronchitis. I also have diabetes.

I used to get the flu shot every year. Four years ago I had a very severe reaction to it and stopped getting it.

There's a few 'logical arguments' which also keep me on the fence about getting a covid vacc.
The first factor is the number of vaccs available. When you get a vacc shot, in the past its "the vacc shot" for that particular condition. You get a flu shot, its "the flu shot" not one formula of many possible formulas. When you get a tetanus shot its "the tetanus shot" not one of multiple formulas. The fact there is not 'one' established, go to formula makes me think something is wrong in all the formulas, otherwise there would only be one.

The next thing is the fact there are so many different strains of covid and its still mutating. Its not like a conveyor belt of covid recipients getting vacc with the same formula. Next, shot, next shot, next, shot.
Plus, you might get the vacc for one strain and 6 months later need to get a different shot for the next regional strain. Plus with no end in sight, there's no telling how many strains might pop up in untold years.

Then there's the red dye #5 scenario. Red dye $5 was used in consumer products until we found out it was bad for you. There used to be lead pain in houses till we found out it was toxic over long duration. Asbestos as well.
Covid vacc is a fast developed, fast distributed fix for a multiple strain mutating pathogen. Its only been a couple years at most. We can't know what the long term effects of these vaccs on the human condition.
Ten years from now are they going to be dealing with a mass population problem caused by these vaccs? Nobody really knows, there hasn't been enough time.

Personally, its fear.
If I get covid, I know it will kill me. My health is bad enough to cause me to wonder if I will survive today let alone years.
If I get the vacc for the current strain, not only might I have adverse reaction to it causing me to die, I could be exposing my body to something on purpose which has the potential to kill me. I'm already doing that by smoking. To me, it would be adding another type of coffin nail to my daily life.

Nothing I've read, watched, heard or consulted convinces me the vacc is safe...for me. I'm not against vaccs. Never had a problem making sure my family was current on their vaccinations, I kept current on mine till 4 years ago.
I just have too many unanswered questions.
I didn't get the bird flu shot.
I didn't get the swine flu shot.
I didn't stop eating beef because of the mad cow's disease.

I see my VA doc in July.
I'll talk with him again about the covid vacc.
If he can alleviate my fears, I'll get the shots.
I just currently believe I should wait till we can see how this is all gunna settle.
Which shot truly is 'the shot'.

no photo
Thu 05/20/21 08:01 PM

My gf goes for her second dose tomorrow.
My son told me he had his second dose a few weeks ago and felt pain in his chest and back for a day or two but it went away on its own.
I don't know which vacc they had.

The VA is pestering me to get mine.
I'm on the fence about the whole thing.
Not only is my health not so good I have respiratory problems like copp and bronchitis. I also have diabetes.

I used to get the flu shot every year. Four years ago I had a very severe reaction to it and stopped getting it.

There's a few 'logical arguments' which also keep me on the fence about getting a covid vacc.
The first factor is the number of vaccs available. When you get a vacc shot, in the past its "the vacc shot" for that particular condition. You get a flu shot, its "the flu shot" not one formula of many possible formulas. When you get a tetanus shot its "the tetanus shot" not one of multiple formulas. The fact there is not 'one' established, go to formula makes me think something is wrong in all the formulas, otherwise there would only be one.

The next thing is the fact there are so many different strains of covid and its still mutating. Its not like a conveyor belt of covid recipients getting vacc with the same formula. Next, shot, next shot, next, shot.
Plus, you might get the vacc for one strain and 6 months later need to get a different shot for the next regional strain. Plus with no end in sight, there's no telling how many strains might pop up in untold years.

Then there's the red dye #5 scenario. Red dye $5 was used in consumer products until we found out it was bad for you. There used to be lead pain in houses till we found out it was toxic over long duration. Asbestos as well.
Covid vacc is a fast developed, fast distributed fix for a multiple strain mutating pathogen. Its only been a couple years at most. We can't know what the long term effects of these vaccs on the human condition.
Ten years from now are they going to be dealing with a mass population problem caused by these vaccs? Nobody really knows, there hasn't been enough time.

Personally, its fear.
If I get covid, I know it will kill me. My health is bad enough to cause me to wonder if I will survive today let alone years.
If I get the vacc for the current strain, not only might I have adverse reaction to it causing me to die, I could be exposing my body to something on purpose which has the potential to kill me. I'm already doing that by smoking. To me, it would be adding another type of coffin nail to my daily life.

Nothing I've read, watched, heard or consulted convinces me the vacc is safe...for me. I'm not against vaccs. Never had a problem making sure my family was current on their vaccinations, I kept current on mine till 4 years ago.
I just have too many unanswered questions.
I didn't get the bird flu shot.
I didn't get the swine flu shot.
I didn't stop eating beef because of the mad cow's disease.

I see my VA doc in July.
I'll talk with him again about the covid vacc.
If he can alleviate my fears, I'll get the shots.
I just currently believe I should wait till we can see how this is all gunna settle.
Which shot truly is 'the shot'.
HI Tom .. I am
Sure there are lots of people that still have reservations about covid vaccines and that is quite understandable . Did you know the first Pfizer vaccine was administered in dec 2020 . So we now have 5 months worth of reliable safety data with little evidence that the pfizer vaccine is harmful . Info surrounding immunity is still being assessed and as time passes more questions will be answered . Pfizer are working on a booster to cover recent mutations .. but that is not surprising to me and does not detract from the efficacy of the vaccine .

Worldwide 1.56 billion people have received a covid vaccine .. that is a great achievement as vaccination rollouts continue to escalate .

As for you personally .. I can understand if you have had past reactions to vaccines why you might be reluctant . Allergic Reactions can vary . If you have had a reaction In the past that required adrenaline .. that would indicate a severe reaction . Such a reaction would occur quickly . Which is why it is important to remain in the clinic for 20 mins following vaccine for monitoring . Vaccinators have the equipment and skills to recognise and treat anaphylaxis should it occur . The risk of a life threatening anaphylaxis really is small .

Some clinics in America are offering allergy testing but for most this is unnecessary and really doesn’t give an absolute guarantee that an allergic reaction will not occur . Have you looked at the Pfizer vaccine ingredients???

Your medical history places you in a high risk group if you were to be infected with covid . Weighing benefits against risk may help you to decide what is in your best interest . Hopefully your own doctor will be able to put your mind at ease .

My experience with covid vaccination. ( Pfizer ) has been positive .

There is high demand for the vaccine in New Zealand ., especially amongst health professionals and front line staff . Rollout of General population vaccination is due to start in June/July but already there are concerns circulating about vaccine shortages .

I am not sure if there are supply issues looming In the states .

Best of luck whatever your decision . Stay well x



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