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Topic: How Do You feel right now? - part 19
SparklingCrystal 💖💎's photo
Thu 02/18/21 03:33 PM


getting really concerned about my mother. She has bloodthinners but they can't ever get her stabile. At the moment the thickness is peaking like a effing idiot from way too thick to way too thin in a very short time.
The schedule and nr of pills they make for her has to be adapted at the mo almost daily. And then it still goes out of whack. She immediately feels it as then her heart does crazy things, she feel unwell etc etc.
Right now it's 4,5 and the top limit is 3. A few days ago it was 1, bottom limit is 2. So it's all over the place in the space of a few days time, no idea why.

So I'm worried.
Hi crystal .. is she taking warfarin ??? A change in INR usually reflects something that happened a few days prior to the change .. for example it takes on average 2 to 5 days for a missed dose to affect INR levels and up to five days to affect the antithrombotic effect .
If her iNR was low then they would seek to increase it to therapeutic levels but because of how it is absorbed and takes affect , it is a bit of a balancing act . I would be more concerned about what caused the drop . Was it picked up on routine screening or did she present feeling unwell .

My concern with a sub therapeutic INR would be the risk of a blood clot (Deep vein thrombosis , pulmonary embolism , cerebrovascular accident )

There are some simple reasons that can cause a drop in. iNR and prothrombin time but also some sinister reasons . It is important to determine what produced the change . Have they taken other blood tests to check her liver , renal and cardiac enzymes .
If they suspect a clot a Ddimer blood test and CTPA scan would help diagnostically .

If she lives alone .. Keep a close eye on her if you can and look after yourself . . Sounds very stressful .


Yes it is stressful indeed. She just contacted me to let me know that she is beginning to feel a bit better so I'm guesstimating it's dropped a bit again.
She's taking acenocoumarol. Not sure of the English word for it, but the half value of it is 11 hours, meaning the working drops after 11 hours and then more after another 11 hours.
My mom reacts like the speed of light. They keep altering her schedule, trying to get her to stabilise. It has been like this ever since she's on them, which is several years, but that the mo it's crazy. And nothing has changed what she eats or does.
She's going to phone the GP tomorrow for an appointment and if possible get to a specialist to have them find out what the heck is causing all this.
Normally she's in touch with the thrombose service but now more is needed and I urged her to see the doc.
And yes, the low INR values are worrying, I don't like it one bit.
She tests herself with a little machine and strips and every so often has to get tested at the thrombose service. I believe every two weeks. But since it fluctuates so often and so much I convinced her to check it herself more often than just once a week or something. Cause often she ends up feeling so unwell and then it's really really out of whack. Best to then find out earlier.
And tonight she tested it, it was 4,5! She phoned thrombose service, they had to consult before giving advice, which was to take 1 pill regardless. She didn't. She daren't as it was already so freaking high.
She is alone, unfortunately, but she has a personal alarm on her. I live 1,5 hrs drive from her, so I can't be of immediate help if something is wrong.

Thank you for helping out!! Much appreciated as I am seriously concerned. She only turned 78 6 days ago, so she's still quite young.
flowerforyou :heart:

no photo
Thu 02/18/21 03:47 PM



getting really concerned about my mother. She has bloodthinners but they can't ever get her stabile. At the moment the thickness is peaking like a effing idiot from way too thick to way too thin in a very short time.
The schedule and nr of pills they make for her has to be adapted at the mo almost daily. And then it still goes out of whack. She immediately feels it as then her heart does crazy things, she feel unwell etc etc.
Right now it's 4,5 and the top limit is 3. A few days ago it was 1, bottom limit is 2. So it's all over the place in the space of a few days time, no idea why.

So I'm worried.
Hi crystal .. is she taking warfarin ??? A change in INR usually reflects something that happened a few days prior to the change .. for example it takes on average 2 to 5 days for a missed dose to affect INR levels and up to five days to affect the antithrombotic effect .
If her iNR was low then they would seek to increase it to therapeutic levels but because of how it is absorbed and takes affect , it is a bit of a balancing act . I would be more concerned about what caused the drop . Was it picked up on routine screening or did she present feeling unwell .

My concern with a sub therapeutic INR would be the risk of a blood clot (Deep vein thrombosis , pulmonary embolism , cerebrovascular accident )

There are some simple reasons that can cause a drop in. iNR and prothrombin time but also some sinister reasons . It is important to determine what produced the change . Have they taken other blood tests to check her liver , renal and cardiac enzymes .
If they suspect a clot a Ddimer blood test and CTPA scan would help diagnostically .

If she lives alone .. Keep a close eye on her if you can and look after yourself . . Sounds very stressful .


Yes it is stressful indeed. She just contacted me to let me know that she is beginning to feel a bit better so I'm guesstimating it's dropped a bit again.
She's taking acenocoumarol. Not sure of the English word for it, but the half value of it is 11 hours, meaning the working drops after 11 hours and then more after another 11 hours.
My mom reacts like the speed of light. They keep altering her schedule, trying to get her to stabilise. It has been like this ever since she's on them, which is several years, but that the mo it's crazy. And nothing has changed what she eats or does.
She's going to phone the GP tomorrow for an appointment and if possible get to a specialist to have them find out what the heck is causing all this.
Normally she's in touch with the thrombose service but now more is needed and I urged her to see the doc.
And yes, the low INR values are worrying, I don't like it one bit.
She tests herself with a little machine and strips and every so often has to get tested at the thrombose service. I believe every two weeks. But since it fluctuates so often and so much I convinced her to check it herself more often than just once a week or something. Cause often she ends up feeling so unwell and then it's really really out of whack. Best to then find out earlier.
And tonight she tested it, it was 4,5! She phoned thrombose service, they had to consult before giving advice, which was to take 1 pill regardless. She didn't. She daren't as it was already so freaking high.
She is alone, unfortunately, but she has a personal alarm on her. I live 1,5 hrs drive from her, so I can't be of immediate help if something is wrong.

Thank you for helping out!! Much appreciated as I am seriously concerned. She only turned 78 6 days ago, so she's still quite young.
flowerforyou :heart:
I mean no disrespect by the following comments ... do you believe she is compliant with taking the medication correctly /consistently ??? Intermittent confusion and aged related memory loss can sometimes cause problems . If you have any doubt of her ability to be self testing and medicating is she eligible for district nursing ? Or similar support services . . Hopefully her doctor /specialist will get to the bottom of what is happening . Ideally that appointment needs to be sooner rather than later . Glad she is starting to feel better crystal waving


SparklingCrystal 💖💎's photo
Thu 02/18/21 03:55 PM




getting really concerned about my mother. She has bloodthinners but they can't ever get her stabile. At the moment the thickness is peaking like a effing idiot from way too thick to way too thin in a very short time.
The schedule and nr of pills they make for her has to be adapted at the mo almost daily. And then it still goes out of whack. She immediately feels it as then her heart does crazy things, she feel unwell etc etc.
Right now it's 4,5 and the top limit is 3. A few days ago it was 1, bottom limit is 2. So it's all over the place in the space of a few days time, no idea why.

So I'm worried.
Hi crystal .. is she taking warfarin ??? A change in INR usually reflects something that happened a few days prior to the change .. for example it takes on average 2 to 5 days for a missed dose to affect INR levels and up to five days to affect the antithrombotic effect .
If her iNR was low then they would seek to increase it to therapeutic levels but because of how it is absorbed and takes affect , it is a bit of a balancing act . I would be more concerned about what caused the drop . Was it picked up on routine screening or did she present feeling unwell .

My concern with a sub therapeutic INR would be the risk of a blood clot (Deep vein thrombosis , pulmonary embolism , cerebrovascular accident )

There are some simple reasons that can cause a drop in. iNR and prothrombin time but also some sinister reasons . It is important to determine what produced the change . Have they taken other blood tests to check her liver , renal and cardiac enzymes .
If they suspect a clot a Ddimer blood test and CTPA scan would help diagnostically .

If she lives alone .. Keep a close eye on her if you can and look after yourself . . Sounds very stressful .


Yes it is stressful indeed. She just contacted me to let me know that she is beginning to feel a bit better so I'm guesstimating it's dropped a bit again.
She's taking acenocoumarol. Not sure of the English word for it, but the half value of it is 11 hours, meaning the working drops after 11 hours and then more after another 11 hours.
My mom reacts like the speed of light. They keep altering her schedule, trying to get her to stabilise. It has been like this ever since she's on them, which is several years, but that the mo it's crazy. And nothing has changed what she eats or does.
She's going to phone the GP tomorrow for an appointment and if possible get to a specialist to have them find out what the heck is causing all this.
Normally she's in touch with the thrombose service but now more is needed and I urged her to see the doc.
And yes, the low INR values are worrying, I don't like it one bit.
She tests herself with a little machine and strips and every so often has to get tested at the thrombose service. I believe every two weeks. But since it fluctuates so often and so much I convinced her to check it herself more often than just once a week or something. Cause often she ends up feeling so unwell and then it's really really out of whack. Best to then find out earlier.
And tonight she tested it, it was 4,5! She phoned thrombose service, they had to consult before giving advice, which was to take 1 pill regardless. She didn't. She daren't as it was already so freaking high.
She is alone, unfortunately, but she has a personal alarm on her. I live 1,5 hrs drive from her, so I can't be of immediate help if something is wrong.

Thank you for helping out!! Much appreciated as I am seriously concerned. She only turned 78 6 days ago, so she's still quite young.
flowerforyou :heart:
I mean no disrespect by the following comments ... do you believe she is compliant with taking the medication correctly /consistently ??? Intermittent confusion and aged related memory loss can sometimes cause problems . If you have any doubt of her ability to be self testing and medicating is she eligible for district nursing ? Or similar support services . . Hopefully her doctor /specialist will get to the bottom of what is happening . Ideally that appointment needs to be sooner rather than later . Glad she is starting to feel better crystal waving



Thank you! And yes, she is very very strict with taking her pills, the time of taking them even. She's set alarms on her phone for her medication to be sure, but she doesn't forget.
It might be difficult to see a doctor tomorrow, short notice, city is always busier, blabla, but she's going to try an emergency spot.
She can also self-test without much problem, only problem is sometimes difficulty getting enough blood. They have the same prob in hospital when they need to take blood, a nightmare. And now she tests so often that her fingers are sore, hihi.
Anywho, hopefully she can see the GP tomorrow. Specialist likely won't happen at that short notice.
Her memory has suffered a wee bit, but not so bad that I think she'd forget her pills.

no photo
Thu 02/18/21 04:49 PM





getting really concerned about my mother. She has bloodthinners but they can't ever get her stabile. At the moment the thickness is peaking like a effing idiot from way too thick to way too thin in a very short time.
The schedule and nr of pills they make for her has to be adapted at the mo almost daily. And then it still goes out of whack. She immediately feels it as then her heart does crazy things, she feel unwell etc etc.
Right now it's 4,5 and the top limit is 3. A few days ago it was 1, bottom limit is 2. So it's all over the place in the space of a few days time, no idea why.

So I'm worried.
Hi crystal .. is she taking warfarin ??? A change in INR usually reflects something that happened a few days prior to the change .. for example it takes on average 2 to 5 days for a missed dose to affect INR levels and up to five days to affect the antithrombotic effect .
If her iNR was low then they would seek to increase it to therapeutic levels but because of how it is absorbed and takes affect , it is a bit of a balancing act . I would be more concerned about what caused the drop . Was it picked up on routine screening or did she present feeling unwell .

My concern with a sub therapeutic INR would be the risk of a blood clot (Deep vein thrombosis , pulmonary embolism , cerebrovascular accident )

There are some simple reasons that can cause a drop in. iNR and prothrombin time but also some sinister reasons . It is important to determine what produced the change . Have they taken other blood tests to check her liver , renal and cardiac enzymes .
If they suspect a clot a Ddimer blood test and CTPA scan would help diagnostically .

If she lives alone .. Keep a close eye on her if you can and look after yourself . . Sounds very stressful .


Yes it is stressful indeed. She just contacted me to let me know that she is beginning to feel a bit better so I'm guesstimating it's dropped a bit again.
She's taking acenocoumarol. Not sure of the English word for it, but the half value of it is 11 hours, meaning the working drops after 11 hours and then more after another 11 hours.
My mom reacts like the speed of light. They keep altering her schedule, trying to get her to stabilise. It has been like this ever since she's on them, which is several years, but that the mo it's crazy. And nothing has changed what she eats or does.
She's going to phone the GP tomorrow for an appointment and if possible get to a specialist to have them find out what the heck is causing all this.
Normally she's in touch with the thrombose service but now more is needed and I urged her to see the doc.
And yes, the low INR values are worrying, I don't like it one bit.
She tests herself with a little machine and strips and every so often has to get tested at the thrombose service. I believe every two weeks. But since it fluctuates so often and so much I convinced her to check it herself more often than just once a week or something. Cause often she ends up feeling so unwell and then it's really really out of whack. Best to then find out earlier.
And tonight she tested it, it was 4,5! She phoned thrombose service, they had to consult before giving advice, which was to take 1 pill regardless. She didn't. She daren't as it was already so freaking high.
She is alone, unfortunately, but she has a personal alarm on her. I live 1,5 hrs drive from her, so I can't be of immediate help if something is wrong.

Thank you for helping out!! Much appreciated as I am seriously concerned. She only turned 78 6 days ago, so she's still quite young.
flowerforyou :heart:
I mean no disrespect by the following comments ... do you believe she is compliant with taking the medication correctly /consistently ??? Intermittent confusion and aged related memory loss can sometimes cause problems . If you have any doubt of her ability to be self testing and medicating is she eligible for district nursing ? Or similar support services . . Hopefully her doctor /specialist will get to the bottom of what is happening . Ideally that appointment needs to be sooner rather than later . Glad she is starting to feel better crystal waving



Thank you! And yes, she is very very strict with taking her pills, the time of taking them even. She's set alarms on her phone for her medication to be sure, but she doesn't forget.
It might be difficult to see a doctor tomorrow, short notice, city is always busier, blabla, but she's going to try an emergency spot.
She can also self-test without much problem, only problem is sometimes difficulty getting enough blood. They have the same prob in hospital when they need to take blood, a nightmare. And now she tests so often that her fingers are sore, hihi.
Anywho, hopefully she can see the GP tomorrow. Specialist likely won't happen at that short notice.
Her memory has suffered a wee bit, but not so bad that I think she'd forget her pills.
the main risk with a high iNR is bleeding . If she develops any signs of bleeding , low blood pressure , dizziness, palpitations or arrhythmias she should present to the emergency clinic and not wait for her appointment . Hopefully the thrombosis Sevice have already instructed her to do that .

SparklingCrystal 💖💎's photo
Thu 02/18/21 04:58 PM
Edited by SparklingCrystal 💖💎 on Thu 02/18/21 04:59 PM

the main risk with a high iNR is bleeding . If she develops any signs of bleeding , low blood pressure , dizziness, palpitations or arrhythmias she should present to the emergency clinic and not wait for her appointment . Hopefully the thrombosis Sevice have already instructed her to do that .

I will ask her tomorrow, it's nearly 2 now, so she's in bed asleep, and so should I be, hihi.
But not sure if the thrombosis services told her that. I have the impression they aren't the brightest people in the world. One told her the other day to take 3 pills cos it was low, the yesterday another said, NOOOOOOO!!! NEVER take 3!!!
And she does get weird feelings and things with her heart. That's one of the ways she knows it's off again.
I'll tell her tomorrow, but I don't want to cause a panic as it's scary enough as it is for her as she knows it's tricky.
For now I can just keep my fingers crossed she can see the doctor tomorrow and that she (the doctor) takes action.
I am very glad she contacts me all the time so at least I can support her.
Thank you for the info and caring!
flowerforyou

AJ70's photo
Fri 02/19/21 03:55 AM
Tired, annoyed, put upon, achy from shoveling and glad its Friday

Rock's photo
Fri 02/19/21 07:50 AM
https://youtu.be/nSAoEf1Ib58


Feelin' groovy.

SparklingCrystal 💖💎's photo
Fri 02/19/21 10:03 AM
Feeling inspired and interested by this course on becoming a wedding official.
I've come across it more often and it appeals to me. I am used to public speaking, am really good at it too (that's what my audiences kept saying), I can write really well so a speech won't be a problem, and what happier thing to do than connect people in marriage?

Cutiepieforyou's photo
Sat 02/20/21 03:40 AM
Good...warming up my car...just about ready to leave for work.

no photo
Sat 02/20/21 07:09 AM
Lionhearted, and simply fantastic!

Stu's photo
Sat 02/20/21 07:11 AM

Lionhearted, and simply fantastic!


Rowr... winking

OT.. cabin feverish

Trixie's photo
Sun 02/21/21 01:02 AM
Fed up with lockdown frustrated

delightfulillusion's photo
Sun 02/21/21 01:03 AM

Fed up with lockdown frustrated


You and me both!

OT Unmotivated

no photo
Sun 02/21/21 02:01 AM
Tired of stupid, mindless messages...

SparklingCrystal 💖💎's photo
Sun 02/21/21 02:09 AM


Fed up with lockdown frustrated


You and me both!

OT Unmotivated

I've had enough of it as well. With the weather improving I want to live normally, go where I want to go. It's been enough.

Stu's photo
Sun 02/21/21 02:10 AM
Tired.. very. F'n. Tired.

no photo
Sun 02/21/21 02:18 AM
It seems everyone needs a hug and cheering up...
(((Group hug))). :heart::sunflower::heart:
I feel very grateful that New Zealand is Covid free, except those in managed isolation. Lockdown was nasty last year. I feel for you guys. Move to New Zealand???
Chin up peeps, Mingle keeps us connected and sane (kind of). :hugging::hugging::hugging:

Stu's photo
Sun 02/21/21 02:20 AM
I'd rather move to an island void of people...

no photo
Sun 02/21/21 02:24 AM
Edited by Unknow on Sun 02/21/21 02:25 AM

I'd rather move to an island void of people...


Stuff your privacy...I am coming too.bigsmile
Ivegotthegirth has a yacht named Ladywind. I think we could convince him to take us all.
Mingle Island :hugging::hugging:

Stu's photo
Sun 02/21/21 02:26 AM


I'd rather move to an island void of people...


Stuff your privacy...I am coming too.bigsmile


laugh it is for other like minded people..

But keep it to yourself.

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