I don't agree with making fun and intentionally offending someone. ..but I also don't agree with editing myself to make sure that what what I say couldn't possibly be taken as an insult.

For example, I say I prefer someone's who's has at least a college degree, I'll get pms stating im insulting anyone without one, and stating that even college graduates are dumb, and many intelligent people don't have degrees etc etc.

Many people (generally those with low self-esteem) take offense at anything, and think tbat you're insulting them.

As far as humor is concerned, who cares it's a joke, get over it. If they're not confident enough in themselves to take a joke, that's their issue not mine.

One of my new favorite quotes is "it's none of my business what other people think about me"

Not every one fits in your question!
The fact must assuage you! :)